TC003

In vitro culture for P vivax

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Principal Investigator (PI)

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Project location

the sponsor

Home Institution

The Barcelona Centre for International Health Research (CRESIB)

foundation funding

Foundation funding

The Foundation is providing £266,850.000 in support.

Open Labs Fellow/s

Richard Thomson - Nuria Antón - Mireia Ferrer

Project Participant/s

Nuria Antón - Richard Thomson

GSK’s contribution

GSK has a group working on the P.vivax culture and the CRESIB and GSK scientists will work in close collaboration. This project will require work in the GSK Biosafety level 3 facilities at Tres Cantos.

Project Description

This two-year project is focused on creating a continuous lab-based supply of the P. vivax malaria parasite in the blood stage. If successful this project will offer a technological breakthrough that could facilitate further advances in research on P. vivax and potentially lead to a new era in P.vivax malaria drug discovery.

Publications 1

Memorias do Instituto Oswaldo Cruz, 108(6)

Red blood cells derived from peripheral blood and bone marrow CD34? human haematopoietic stem cells are permissive to Plasmodium parasites infection

Fernandez-Becerra, C., Lelievre, J., Ferrer, M., Anton, N., Thomson, R., Peligero, C., Almela, M. J., Lacerda, M. V., Herreros, E., & Del Portillo, H. A.

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